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True or False:
BCG is a vaccine for TB that is widely used in the United States.
The medicine usually used for LTBI is a drug called isoniazid, or INH. INH kills the TB bacteria that are inactive in the body. LTBI treatment will keep the individual from ever developing TB disease. Standard INH treatment lasts for 9 months. Sometimes people are given LTBI treatment even if their TB test reaction is not positive. This is often done with infants, children, and HIV-infected people who have recently spent time with someone with infectious TB disease because they are at very high risk of developing serious TB disease soon after they become infected with TB bacteria. BCG is a vaccine for TB. This vaccine is not widely used in the United States, but it is often given to infants and small children in other countries where TB is common. BCG vaccine does not always protect people from TB. Individuals vaccinated with BCG may have a positive reaction to a TB skin test. This reaction may be due to the BCG vaccine itself or to a real TB infection.
One of the signs of a true or positive TB infection is that the ______________ is large.
BCG is a vaccine for TB. This vaccine is not widely used in the United States, but it is often given to infants and small children in other countries where TB is common. BCG vaccine does not always protect people from TB. Individuals vaccinated with BCG may have a positive reaction to a TB skin test. This reaction may be due to the BCG vaccine itself or to a real TB infection. Signs of a true or positive TB infection include: The skin test reaction is large. The individual was vaccinated many years ago (because the BCG reaction gets smaller over time). The individual has spent time with a person with infectious TB. Someone in the family has TB. The person is from a country where TB disease is very common (most countries in Latin America, and the Caribbean, Africa, and Asia, except for Japan).
To avoid the development of resistant TB, patients typically take TB medications under the supervision of health workers, a method known as _________________, or DOT.
If TB patients in treatment do not take each medication at the prescribed time or are unable to complete the full course of treatment, their tuberculosis may become resistant to those medications. To avoid the development of resistant TB, patients typically take TB medications under the supervision of health workers, a method known as Directly Observed Therapy, or DOT. Over the past 15 years, however, incomplete TB treatments — due to shortages of medicines and medical personnel, civil disruptions, and socioeconomic barriers for patients — have led to a proliferation of strains of tuberculosis resistant to two or more TB medications. These strains, known as multi-drug resistant tuberculosis, or MDR-TB, are now present throughout the world. If left untreated MDR-TB not only kills the patients but can spread to other people, where it may develop additional drug resistance.
True or False:
A proliferation of strains of tuberculosis are resistant to two or more TB medications. These strains, known as multi-drug resistant tuberculosis, or MDR-TB, are now present only in the United States.
Over the past 15 years, however, incomplete TB treatments — due to shortages of medicines and medical personnel, civil disruptions, and socioeconomic barriers for patients — have led to a proliferation of strains of tuberculosis resistant to two or more TB medications. These strains, known as multi-drug resistant tuberculosis, or MDR-TB, are now present throughout the world. If left untreated MDR-TB not only kills the patients but can spread to other people, where it may develop additional drug resistance. Extremely virulent strains of tuberculosis (XDR-TB) that are resistant to three or more of the second-line drugs used to treat MDR-TB have reached epidemic proportions in Africa. One outbreak in KwaZulu-Natal, South Africa, killed 74 of 78 patients within a matter of weeks, sparking fears that XDR-TB could spread rapidly and lethally, particularly in areas with high prevalence of HIV infection. In September 2006 the World Health Organization issued an alert regarding the emergence of XDR-TB.
Extremely virulent strains of tuberculosis (XDR-TB) that are resistant to three or more of the second-line drugs used to treat MDR-TB have reached epidemic proportions in _________________.
Over the past 15 years, however, incomplete TB treatments — due to shortages of medicines and medical personnel, civil disruptions, and socioeconomic barriers for patients — have led to a proliferation of strains of tuberculosis resistant to two or more TB medications. These strains, known as multi-drug resistant tuberculosis, or MDR-TB, are now present throughout the world. If left untreated MDR-TB not only kills the patients but can spread to other people, where it may develop additional drug resistance. Extremely virulent strains of tuberculosis (XDR-TB) that are resistant to three or more of the second-line drugs used to treat MDR-TB have reached epidemic proportions in Africa. One outbreak in KwaZulu-Natal, South Africa, killed 74 of 78 patients within a matter of weeks, sparking fears that XDR-TB could spread rapidly and lethally, particularly in areas with high prevalence of HIV infection. In September 2006 the World Health Organization issued an alert regarding the emergence of XDR-TB.
True or False:
The medicine usually used for LTBI is a drug called isoniazid or INH. INH kills the TB bacteria that are inactive in the body.
BCG is a vaccine for TB. This vaccine is not widely used in the United States, but it is often given to infants and small children in other countries where TB is common. BCG vaccine does not always protect people from TB. Individuals vaccinated with BCG may have a positive reaction to a TB skin test. This reaction may be due to the BCG vaccine itself or to a real TB infection. The medicine usually used for LTBI is a drug called isoniazid, or INH. INH kills the TB bacteria that are inactive in the body. LTBI treatment will keep the individual from ever developing TB disease. Standard INH treatment lasts for 9 months. Sometimes people are given LTBI treatment even if their TB test reaction is not positive. This is often done with infants, children, and HIV-infected people who have recently spent time with someone with infectious TB disease because they are at very high risk of developing serious TB disease soon after they become infected with TB bacteria.
True or False:
LTBI treatment will keep the individual from developing TB disease for one year.
The medicine usually used for LTBI is a drug called isoniazid, or INH. INH kills the TB bacteria that are inactive in the body. LTBI treatment will keep the individual from ever developing TB disease. Standard INH treatment lasts for 9 months. Sometimes people are given LTBI treatment even if their TB test reaction is not positive. This is often done with infants, children, and HIV-infected people who have recently spent time with someone with infectious TB disease because they are at very high risk of developing serious TB disease soon after they become infected with TB bacteria. Very few people have serious side effects to INH.
The only Asian country where TB is not common is:
BCG is a vaccine for TB. This vaccine is not widely used in the United States, but it is often given to infants and small children in other countries where TB is common. BCG vaccine does not always protect people from TB. Individuals vaccinated with BCG may have a positive reaction to a TB skin test. This reaction may be due to the BCG vaccine itself or to a real TB infection. Signs of a true or positive TB infection include: The skin test reaction is large. The individual was vaccinated many years ago (because the BCG reaction gets smaller over time). The individual has spent time with a person with infectious TB. Someone in the family has TB. The person is from a country where TB disease is very common (most countries in Latin America and the Caribbean, Africa, and Asia, except for Japan). The Quantiferon-TB Gold Test detects true LTBI and does not react to BCG.
Standard INH treatment lasts for:
The medicine usually used for LTBI is a drug called isoniazid, or INH. INH kills the TB bacteria that are inactive in the body. LTBI treatment will keep the individual from ever developing TB disease. Standard INH treatment lasts for 9 months. Sometimes people are given LTBI treatment even if their TB test reaction is not positive. This is often done with infants, children, and HIV-infected people who have recently spent time with someone with infectious TB disease because they are at very high risk of developing serious TB disease soon after they become infected with TB bacteria. Very few people have serious side effects to INH; however, if any of the following side effects are experienced, a doctor should be seen right away:
No appetite
Nausea
Vomiting
Yellowish skin or eyes
Fever for more than three days
Abdominal pain
Tingling in the fingers and toes
Drinking ___________________ while taking INH can be dangerous.
Very few people have serious side effects to INH; however, if any of the following side effects are experienced, a doctor should be seen right away:
No appetite
Nausea
Vomiting
Yellowish skin or eyes
Fever for more than three days
Abdominal pain
Tingling in the fingers and toes
Warning: Drinking alcoholic beverages (wine, beer, and liquor) while taking INH can be dangerous. BCG is a vaccine for TB. This vaccine is not widely used in the United States, but it is often given to infants and small children in other countries where TB is common. BCG vaccine does not always protect people from TB.